Publications
2023
Impact of the lipase inhibitor orlistat on the human gut microbiota
Uehira Y, Ueno H, Miyamoto J, Kimura I, Ishizawa Y, Iijima H, Muroga S, Fujita T, Sakai S, Samukawa Y, Tanaka Y, Murayama S, Sakoda H, Nakazato M.
Obes Res Clin Pract. 2023 Sep-Oct;17(5):411-420.
2023
https://www.sciencedirect.com/science/article/pii/S1871403X23000704
Exome-wide benchmark of difficult-to-sequence regions using short-read next-generation DNA sequencing
Hijikata A, Suyama M, Kikugawa S, Matoba R, Naruto T, Enomoto Y, Kurosawa K, Harada N, Yanagi K, Kaname T, Miyako K, Takazawa M, Sasai H, Hosokawa J, Itoga S, Yamaguchi T, Kosho T, Matsubara K, Kuroki Y, Fukami M, Adachi K, Nanba E, Tsuchida N, Uchiyama Y, Matsumoto N, Nishimura K, Ohara O.
Nucleic Acids Res. 2023 Nov 28:gkad1140.
2023
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad1140/7453260
2021
Associations of LRP5 and MTHFR Gene Variants with Osteoarthritis Prevalence in Elderly Women: A Japanese Cohort Survey Randomly Sampled from a Basic Resident Registry.
Nakano M, Yui H, Kikugawa S, Tokida R, Sakai N, Kondo N, Endo N, Haro H, Shimodaira H, Suzuki T, Kato H, Takahashi J, Nakamura Y.
Ther Clin Risk Manag. 2021;17:1065-1073
2021
https://doi.org/10.2147/TCRM.S330530
EML4-ALK fusion variant.3 and co-occurrent PIK3CA E542K mutation exhibiting primary resistance to three generations of ALK inhibitors.
Kunimasa K, Hirotsu Y, Kukita Y, Ueda Y, Sato Y, Kimura M, Otsuka T, Hamamoto Y, Tamiya M, Inoue T, Kawamura T, Nishino K, Amemiya K, Goto T, Mochizuki H, Honma K, Omata M, Kumagai T.
Cancer Genet. 2021 May 28;256-257:131-135.
2021
https://www.sciencedirect.com/science/article/abs/pii/S2210776221001162
STK11 loss drives rapid progression in a breast cancer patient resulting in pulmonary tumor thrombotic microangiopathy.
Fujisawa F, Kunimasa K, Kano-Fujiwara R, Sato Y, Kusama H, Nishio M, Matsui S, Yoshinami T, Kittaka N, Nakamura H, Nagata S, Honma K, Yagi T, Nakayama T, Tamaki Y, Imamura F.
Breast Cancer. 2021 May;28(3):765-771.
2021
https://link.springer.com/article/10.1007/s12282-020-01200-1
2020
Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors.
Nakatake Y, Ko SBH, Sharov AA, Wakabayashi S, Murakami M, Sakota M, Chikazawa N, Ookura C, Sato S, Ito N, Ishikawa-Hirayama M, Mak SS, Jakt LM, Ueno T, Hiratsuka K, Matsushita M, Goparaju SK, Akiyama T, Ishiguro KI, Oda M, Gouda N, Umezawa A, Akutsu H, Nishimura K, Matoba R, Ohara O, Ko MSH.
Cell Rep. 2020 May 19;31(7):107655.
2020
https://linkinghub.elsevier.com/retrieve/pii/S2211-1247(20)30608-2
Observation of p.R4810K, a Polymorphism of the Mysterin Gene, the Susceptibility Gene for Moyamoya Disease, in Two Female Japanese Diabetic Patients with Familial Partial Lipodystrophy 1.
Iwanishi M, Azuma C, Tezuka Y, Yamamoto Y, Ito-Kobayashi J, Washiyama M, Kusakabe T, Kikugawa S.
Intern Med. 2020;59(20):2529-2537.
2020
https://www.jstage.jst.go.jp/article/internalmedicine/59/20/59_4042-19/_article
Identification of molecules associated with response to abatacept in patients with rheumatoid arthritis.
Yokoyama-Kokuryo W, Yamazaki H, Takeuchi T, Amano K, Kikuchi J, Kondo T, Nakamura S, Sakai R, Hirano F, Nanki T, Koike R, Harigai M.
Arthritis Res Ther. 2020 Mar 12;22(1):46.
2020
https://doi.org/10.1186/s13075-020-2137-y
2019
DELIVER (JACCRO GC-08) trial: discover novel host-related immune-biomarkers for nivolumab in advanced gastric cancer.
Sunakawa Y, Inoue E, Matoba R, Kawakami H, Sato Y, Nakajima TE, Muro K, Ichikawa W. And Fujii M.
Future Oncol. 2019 Jul;15(21):2441-2447.
2019
https://doi.org/10.2217/fon-2019-0167
Detection of gene mutations in gastric cancer tissues using a commercial sequencing panel.
Ito T, Matoba R, Maekawa H, Sakurada M, Kushida T, Orita H, Wada R, Sato K.
Molecular and Clinical Oncology 11: 455-460, 2019
2019
https://www.spandidos-publications.com/mco/11/5/455/abstract
Combined surgery and chondrocyte cell-sheet transplantation improves clinical and structural outcomes in knee osteoarthritis.
Sato M, Yamato M, Mitani G, Takagaki T, Hamahashi K, Nakamura Y, Ishihara M, Matoba R, Kobayashi H, Okano T, Mochida J, Watanabe M.
npj Regenerative Medicine volume 4, Article number: 4 (2019) 2019
http://www.nature.com/articles/s41536-019-0069-4
Recent Advances in Liquid Biopsy in Precision Oncology Research.
Sato Y, Matoba R, Kato K.
Biol Pharm Bull. 2019;42(3):337-342
2019
https://doi.org/10.1248/bpb.b18-00804
Practical determination of LODP (limit of detection for microarray platform) for the evaluation of microarray platforms.
Adachi S, Aoki H, Ueda Y, Sudo T, Nozawa A, Koga S, Suzuki H, Shibayama S, Noda N, Fujii SI, Itoh S, Kawashima S, Suda Y, Nakae H.
Anal Biochem. 2019 Oct 15;583:113360
2019
https://www.sciencedirect.com/science/article/abs/pii/S0003269719303872?via%3Dihub
2018
Olfactomedin-like protein OLFML1 inhibits Hippo signaling and mineralization in osteoblasts.
Murakami K, Kikugawa S, Kobayashi Y, Uehara S, Suzuki T, Kato H, Udagawa N, Nakamura Y.
Biochemical and Biophysical Research Communications, Volume 505, Issue 2, 2018, Pages 419-425
2018
https://doi.org/10.1016/j.bbrc.2018.09.112
Identification of baseline gene expression signatures predicting therapeutic effects of TNF inhibitors in rheumatoid arthritis patients.
Nakamura S, Suzuki K, Kaneko Y, Takeuchi T, Amano K
Clin Rheumatol Rel Res. 30: 300-307, 2018
2018
https://doi.org/10.1186/s13075-016-1052-8
FGF23 modulates the effects of erythropoietin on gene expression in renal epithelial cells.
Yashiro M, Ohya M, Mima T, Ueda Y, Nakashima Y, Kawakami K, Ishizawa Y, Yamamoto S, Kobayashi S, Yano T, Tanaka Y, Okuda K, Sonou T, Shoshihara T, Iwashita Y, Iwashita Y, Tatsuta K, Matoba R, Negi S, Shigematsu T
Int J Nephrol Renovasc Dis. 2018:11 125-136.
2018
https://www.dovepress.com/fgf23-modulates-the-effects-of-erythropoietin-on-gene-expression-in-re-peer-reviewed-article-IJNRD
Integrated profiling of phenotype and blood transcriptome for stress vulnerability and depression.
Hori H, Nakamura S, Yoshida F, Teraishi T, Sasayama D, Ota M, Hattori K, Kim Y, Higuchi T, Kunugi H.
J Psychiatr Res. 2018 Sep;104:202-210.
2018
https://www.sciencedirect.com/science/article/pii/S0022395618306101
2017
Copy number loss in the region of ASPN gene in patients with acetabular dysplasia.
Sekimoto T, Ishii M, Emi M, Kurogi S, Funamoto T, Hamada H, Chosa E.
Bone & Joint Res 2017 (in press)
2017
https://online.boneandjoint.org.uk/doi/full/10.1302/2046-3758.67.BJR-2016-0094.R1
Distinct transcriptional and metabolic profiles associated with empathy in Buddhist priests: a pilot study.
Ohnishi J, Ayuzawa S, Nakamura S, Sakamoto S, Hori M, Sasaoka T, Takimoto-Ohnishi E, Tanatsugu M and Murakami K.
Human Genomics 2017 11:22.
2017
https://humgenomics.biomedcentral.com/articles/10.1186/s40246-017-0117-3
Whole-exome sequencing and digital PCR identified a novel compound heterozygous mutation in NPHP1 gene inn a case of Joubert syndrome and related disorders.
Koyama S, Sato H, Kawakami T, Emi M, Kato T.
BMC Med Genetics, 2017, 37-41 2017
https://bmcmedgenet.biomedcentral.com/articles/10.1186/s12881-017-0399-2
2016
Assessment of the Safety of Chondrocyte Sheet Implantation for Cartilage Regeneration.
Yokoyama M, Sato M, Umezawa A, Mitani G, Takagaki T, Yokoyama M, Kawake T, Okada E, Kokubo M, Ito N, Takaku Y, Murai K, Matoba R, Akutsu H, Yamato M, Okano T, Mochida J
Tissue Eng Part C Methods. 2016 Jan;22(1):59-68.
2016
http://online.liebertpub.com/doi/abs/10.1089/ten.TEC.2015.0254?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&
Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses.
ori H, Sasayama D, Teraishi T, Yamamoto N, Nakamura S, Ota M, Hattori K, Kim Y, Higuchi T, Kunugi H.
Sci Rep. 2016 Jan 5;6:18776.
2016
http://www.nature.com/articles/srep18776
High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma.
Yoshikawa Y, Emi M, Hashimoto-Tamaoki T, Ohmuraya M, Sato A, Tsujimura T, Hasegawa S, Nakano T, Nasu M, Pastorino S, Szymiczek A, Bononi A, Tanji M, Pagano I, Gaudino G, Napolitano A, Goparaju C, Pass HI, Yang H, Carbone M.
Proc. National. Acad. Sci. USA: November 9, 2016.
2016
http://www.pnas.org/content/113/47/13432.long
Identification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study.
Nakamura S, Suzuki K, Iijima H, Hata Y, Lim CR, Ishizawa Y, Kameda H, Amano K, Matsubara K, Matoba R, Takeuchi T.
Arthritis Research & Therapy. 2016 Jul 19;18:159.
2016
https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-016-1052-8
Impact of visceral fat on gene expression profile in peripheral blood cells in obese Japanese subjects.
Obata Y, Maeda N,Yamada Y, Yamamoto K, Nakamura S, Yamaoka M, Tanaka Y, Masuda S, Nagao H, Fukuda S, Fujishima Y, Kita S,Nishizawa H, Funahashi T,Matsubara KI, Matsuzawa Y, Shimomura
Cardiovasc Diabetol. 2016 Nov 29;15(1):159.
2016
https://cardiab.biomedcentral.com/articles/10.1186/s12933-016-0479-1
Profiling of exercise-induced transcripts in the peripheral blood cells of Thoroughbred horses.
Tozaki T, Kikuchi M, Kakoi H, Hirota KI, Mukai K, Aida H, Nakamura S, Nagata SI
J Equine Sci. 2016;27(4):157-164.
2016
https://www.jstage.jst.go.jp/article/jes/27/4/27_1616/_article
2015
miR-340 suppresses the stem-like cell function of glioma-initiating cells by targeting tissue plasminogen activator.
Yamashita D, Kondo T, Ohue S, Takahashi H, Ishikawa M, Matoba R, Suehiro S, Kohno S, Harada H, Tanaka J. and Ohnishi T.
Cancer Res. 75(6) (2015) 1123-1133.
2015
https://cancerres.aacrjournals.org/content/75/6/1123.long
A set of external reference controls/probes that enable quality assurance between different microarray platforms.
Akiyama H, Ueda Y, Nobumasa H, Ooshima H, Ishizawa Y, Kitahiro K, Miyagawa I, Watanabe K, Nakamura T, Tanaka R, Yamamoto N, Nakae H, Kawase M, Gemma N, Sekiguchi Y, Fujibuchi W, Matoba R.
Anal Biochem. 2015 Mar 1;472:75-83.
2015
http://www.sciencedirect.com/science/article/pii/S0003269714005417
Chlorella ingestion suppresses resistin gene expression in peripheral blood cells of borderline diabetics.
Itakura H, Kobayashi M, Nakamura S
Clinical Nutrition ESPEN Volume 10, Issue 3, June 2015, Pages e95-e101
2015
http://www.clinicalnutritionespen.com/article/S2405-4577(15)00096-0/fulltext
Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s.
Carbone M, Flores EG, Emi M, Johnson TA, Tsunoda T, Behner D, Hoffman H, Hesdorffer M, Nasu M, Napolitano A, Powers A, Minaai M, Baumann F, Bryant-Greenwood P, Lauk O, Kirschner MB, Weder W, Opitz I, Pass HI, Gaudino G, Pastorino S, Yang H.
PLoS Genet. 2015 Dec 18;11(12):e1005633.
2015
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005633
Frequent genomic rearrangements of BRCA1 associated protein-1 (BAP1) gene in Japanese malignant mesothelioma-characterization of deletions at exon level.
Emi M, Yoshikawa Y, Sato C, Sato A, Sato H, Kato T, Tsujimura T, Hasegawa S, Nakano T, Hashimoto-Tamaoki T.
J Hum Genet. 2015 Oct;60(10):647-9.
2015
https://doi.org/10.1038/jhg.2015.91
High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma.
Nasu M, Emi M, Pastorino S, Tanji M, Powers A, Luk H, Baumann F, Zhang YA, Gazdar A, Kanodia S, Tiirikainen M, Flores E, Gaudino G, Becich MJ, Pass HI, Yang H, Carbone M.
J Thorac Oncol. 2015 Apr;10(4):565-76.
2015
http://www.jto.org/article/S1556-0864(15)32358-3/fulltext
High-fidelity target sequencing of individual molecules identified using barcode sequences: de novo detection and absolute quantitation of mutations in plasma cell-free DNA from cancer patients.
Kukita Y, Matoba R, Uchida J, Hamakawa T, Doki Y, Imamura F, Kato K.
DNA Res. 2015 Aug;22(4):269-77.
2015
https://academic.oup.com/dnaresearch/article-lookup/doi/10.1093/dnares/dsv010
Identification of Individual Cancer-Specific Somatic Mutations for Neoantigen-Based Immunotherapy of Lung Cancer.
Karasaki T, Nagayama K, Kawashima M, Hiyama N, Murayama T, Kuwano H, Nitadori JI, Anraku M, Sato M, Miyai M, Hosoi A, Matsushita H, Kikugawa S, Matoba R, Ohara O, Kakimi K, Nakajima J.
J Thorac Oncol. 2015 Dec 29. pii: S1556-0864(15)00076-3.
2015
http://www.jto.org/article/S1556-0864(15)00076-3/fulltext
Imbalance between the expression dosages of X-chromosome and autosomal genes in mammalian oocytes.
Fukuda A, Tanino M, Matoba R, Umezawa A, Akutsu H.
Sci Rep. 2015 Sep 15;5:14101.
2015
http://www.nature.com/articles/srep14101
PCSK5 mutation in a patient with the VACTERL association.
Nakamura Y, Kikugawa S, Seki S, Takahata M, Iwasaki N, Terai H, Matsubara M, Fujioka F, Inagaki H, Kobayashi T, Kimura T, Kurahashi H, Kato H.
BMC Res Notes. 2015 Jun 9;8:228.
2015
https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-015-1166-0
Somatic alteration and depleted nuclear expression of BAP1 in human esophageal squamous cell carcinoma.
Mori T, Sumii M, Fujishima F, Ueno K, Emi M, Nagasaki M, Ishioka C, Chiba N.
Cancer Sci. 2015 Sep;106(9):1118-29.
2015
http://onlinelibrary.wiley.com/doi/10.1111/cas.12722/abstract
2014
Duodenal follicular lymphoma: comprehensive gene expression analysis with insights into pathogenesis.
Takata K, Tanino M, Ennishi D, Tari A, Sato Y, Okada H, Maeda Y, Goto N, Araki H, Harada M, Ando M, Iwamuro M, Tanimoto M, Yamamoto K, Gascoyne RD, Yoshino T.
Cancer Sci. 2014 May;105(5):608-15
2014
https://doi.org/10.1111/cas.12392
Increased Protein and mRNA Expression of Resistin After Dexamethasone Administration.
Sasayama D, Hori H, Nakamura S, Yamamoto N, Hattori K, Teraishi T, Ota M, Kunugi H
Horm Metab Res. 2014 Jul 10.
2014
https://www.thieme-connect.com/DOI/DOI?10.1055/s-0034-1383651
ITIH3 polymorphism may confer susceptibility to psychiatric disorders by altering the expression levels of GLT8D1.
Sasayama D, Hori H, Yamamoto N, Nakamura S, Teraishi T, Tatsumi M, Hattori K, Ota M, Higuchi T, Kunugi H.
J Psychiatr Res. 2014 Mar;50:79-83.
2014
http://www.journalofpsychiatricresearch.com/article/S0022-3956(13)00368-3/fulltext
Large-Scale East-Asian eQTL Mapping Reveals Novel Candidate Genes for LD Mapping and the Genomic Landscape of Transcriptional Effects of Sequence Variants.
Narahara M, Higasa K, Nakamura S, Tabara Y, Kawaguchi T, Ishii M, Matsubara K, Matsuda F, Yamada R1.
PLoS One. 2014 Jun 23;9(6):e100924.
2014
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100924
2013
Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation (Peripheral blood S100 mRNAs and metabolic syndrome).
Yamaoka M, Maeda N, Nakamura S, Mori T, Inoue K, Matsuda K, Sekimoto R, Kashine S, Nakagawa Y, Tsushima Y, Fujishima Y, Komura N, Hirata A, Nishizawa H, Matsuzawa Y, Matsubara K, Funahashi T, Shimomura I
Biochem Biophys Res Commun. 2013 Apr 19;433(4):450-5.
2013
http://www.sciencedirect.com/science/article/pii/S0006291X13004014
Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells.
Li Y, Drnevich J, Akraiko T, Band M, Li D, Wang F, Matoba R, Tanaka TS.
Genomics. 2013 Nov-Dec;102(5-6):456-67.
2013
http://www.sciencedirect.com/science/article/pii/S0888754313001857
Identification of single nucleotide polymorphisms regulating peripheral blood mRNA expression with genome-wide significance: an eQTL study in the Japanese population.
Sasayama D, Hori H, Nakamura S, Miyata R, Teraishi T, Hattori K, Ota M, Yamamoto N, Higuchi T, Amano N, Kunugi H.
PLoS One. 2013;8(1):e54967.
2013
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054967
Low gene expression levels of activating receptors of natural killer cells (NKG2E and CD94) in patients with fulminant type 1 diabetes.
Nakata S, Imagawa A, Miyata Y, Yoshikawa A, Kozawa J, Okita K, Funahashi T, Nakamura S, Matsubara K, Iwahashi H, Shimomura I
Immunol Lett. 2013 Nov-Dec;156(1-2):149-55.
2013
http://www.sciencedirect.com/science/article/pii/S0165247813001636
Segmental copy number loss in the region of Semaphorin 4D gene in patients with acetabular dysplasia.
Sekimoto T, Ishii M, Emi M, Kurogi S, Funamoto T, Hamada H, Chosa E.
J Orthop Res. 2013 Jun;31(6):957-61.
2013
http://onlinelibrary.wiley.com/doi/10.1002/jor.22310/abstract
Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles.
Hikichi T1, Matoba R, Ikeda T, Watanabe A, Yamamoto T, Yoshitake S, Tamura-Nakano M, Kimura T, Kamon M, Shimura M, Kawakami K, Okuda A, Okochi H, Inoue T, Suzuki A, Masui S.
Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6412-7.
2013
http://www.pnas.org/content/110/16/6412.long
2012
Large-scale genome reorganization in Saccharomyces cerevisiae through combinatorial loss of mini-chromosomes.
Ueda Y, Ikushima S, Sugiyama M, Matoba R, Kaneko Y, Matsubara K. and Harashima S.
J Biosci Bioeng. Jun;113 (2012) 675-682.
2012
http://dx.doi.org/10.1016/j.jbiosc.2012.01.013
Genome-Wide Analysis of DNA Methylation and Expression of MicroRNAs in Breast Cancer Cells.
Morita S, Takahashi R, Yamashita R, Toyoda A, Horii, T, Kimura M, Fujiyama A, Nakai K, Tajima S, Matoba R, Ochiya T. and Hatada I.
Int. J. Mol. Sci. 13 (2012) 8259-8272.
2012
https://dx.doi.org/10.3390%2Fijms13078259
A Pilot Investigation of Visceral Fat Adiposity and Gene Expression Profile in Peripheral Blood Cells.
Yamaoka M, Maeda N, Nakamura S, Kashine S, Nakagawa Y, Hiuge-Shimizu A, Okita K, Imagawa A, Matsuzawa Y, Matsubara K, Funahashi T, Shimomura I.
PLoS One. 2012;7(10):e47377.
2012
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047377
Frequent inactivation of BAP1 gene in epithelioid-type malignant mesothelioma.
Yoshikawa Y, Sato A, Tsujimura T, Emi M, Morinaga T, Fukuoka K, Yamada S, Murakami A, Kondo N, Matsumoto S, Okumura Y, Tanaka F, Hasegawa S, Nakano T, Hashimoto-Tamaoki T
Cancer Sci. 2012 May;103(5):868-74
2012
http://onlinelibrary.wiley.com/doi/10.1111/j.1349-7006.2012.02223.x/abstract
Genome-wide copy number analysis in primary breast cancer.
Ueno T, Emi M, Sato H, Ito N, Muta M, Kuroi K, Toi M
Expert Opin Ther Targets. 2012 Mar;16 Suppl 1:S31-5
2012
http://www.tandfonline.com/doi/full/10.1517/14728222.2011.636739
Identification of blood biomarkers of aging by transcript profiling of whole blood.
Nakamura S, Kawai K, Takeshita Y, Honda M, Takamura T, Kaneko S, Matoba R, Matsubara K
Biochem Biophys Res Commun. 2012 Feb 10;418(2):313-8.
2012
http://www.sciencedirect.com/science/article/pii/S0006291X12000411
2011
Heterogeneity of colorectal cancers and extraction of discriminator gene signatures for personalized prediction of prognosis.
Miyake M, Takemasa I, Matoba R, Tanino M, Niijima S, Ikeda M, Yamamoto H, Sekimoto M, Kuhara S, Okayama T, Monden M, Matsubara K. and Mori M.
Int J Oncol. 39 (2011) 781-789.
2011
http://dx.doi.org/10.3892/ijo.2011.1092
Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy.
Sasaki H, Emi M, Iijima H, Ito N, Sato H, Yabe I, Kato T, Utsumi J, Matsubara K.
Mol Brain. 2011 Jun 10;4:24.
2011
https://molecularbrain.biomedcentral.com/articles/10.1186/1756-6606-4-24
Frequent loss of genome gap region in 4p16.3 subtelomere in early-onset type 2 diabetes mellitus.
Kudo H, Emi M, Ishigaki Y, Tsunoda U, Hinokio Y, Ishii M, Sato H, Yamada T, Katagiri H, Oka Y.
Exp Diabetes Res. 2011;2011:498460.
2011
https://www.hindawi.com/journals/jdr/2011/498460/
Influence of Chlorella powder intake during swimming stress in mice.
Mizoguchi T, Arakawa Y, Kobayashi M, Fujishima M.
Biochem Biophys Res Commun. 2011 Jan 7;404(1):121-6.
2011
http://www.sciencedirect.com/science/article/pii/S0006291X10021443
Molecular analysis of TSC2/PKD1 contiguous gene deletion syndrome.
Oyazato Y, Iijima K, Emi M, Sekine T, Kamei K, Takanashi J, Nakao H, Namai Y, Nozu K, Matsuo M
Kobe J. Med. Sci. 2011; 57: 1.
2011
http://www.med.kobe-u.ac.jp/journal/contents/57/E1.pdf
Segmental copy number loss of SFMBT1 gene in elderly individuals with ventriculomegaly: a community-based study.
Kato T, Sato H, Emi M, Seino T, Arawaka S, Iseki C, Takahashi Y, Wada M, Kawanami T.
Intern Med. 2011;50(4):297-303. Epub 2011 Feb 15.
2011
https://www.jstage.jst.go.jp/article/internalmedicine/50/4/50_4_297/_article
Spread of X-chromosome inactivation into chromosome 15 is associated with Prader-Willi syndrome phenotype in a boy with a t(X;15)(p21.1;q11.2) translocation.
Sakazume S, Ohashi H, Sasaki Y, Harada N, Nakanishi K, Sato H, Emi M, Endoh K, Sohma R, Kido Y, Nagai T, Kubota T.
J Human Genet, 2011 Epub Jul 7
<2011br>
https://link.springer.com/article/10.1007%2Fs00439-011-1051-4
2010
Copy number variation: experimental procedures and statistical analysis.
Sato H, Emi M.
Nippon Rinsho. 2010 Aug;68(8):76-9.
2010
http://www.nippon-rinsho.co.jp/backnum/z_mokuji/6808idensi.html
Effect of exercise on gene expression profile in unfractionated peripheral blood leukocytes.
Nakamura S, Kobayashi M, Sugino T, Kajimoto O, Matoba R, Matsubara K.
Biochem Biophys Res Commun. 2010 Jan 1;391(1):846-51.
2010
http://www.sciencedirect.com/science/article/pii/S0006291X09023468
HNF1B Alterations Associated with Congenital Anomalies of the Kidney and Urinary Tract.
Nakayama M, Nozu K, Goto Y, Kamei K, Ito S, Sato H, Emi M, Nakanishi K, Tsuchiya S, Iijima K
Pediatr Nephrol. 2010 Jun;25(6):1073-9.
2010
https://link.springer.com/article/10.1007%2Fs00467-010-1454-9
Segmental copy-number gain within the region of isopentenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis.
Kato T, Emi M, Sato H, Arawaka S, Wada M, Kawanami T, Katagiri T, Tsuburaya K, Toyoshima I, Tanaka F, Sobue G, Matsubara K.
Biochem Biophys Res Commun. 2010 Nov 12;402(2):438-42.
2010
http://www.sciencedirect.com/science/article/pii/S0006291X10019339
The novel and independent association between single-point SNP of NPHP4 gene and renal function in non-diabetic Japanese population: the Takahata study.
Konta T, Takasaki S, Ichikawa K, Emi M, Toriyama S, Satoh H, Ikeda A, Suzuki K, Mashima Y, Shibata Y, Watanabe T, Kato T, Kawata S, Kubota I.
J Hum Genet. 2010 Sep 16.
2010
https://doi.org/10.1038/jhg.2010.113
Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal.
Yang D, Yaguchi T, Lim CR, Ishizawa Y, Nakano T, Nishizaki T.
Cancer Lett. 2010 May 28;291(2):225-9.
2010
http://www.cancerletters.info/article/S0304-3835(09)00638-7/fulltext
Various types of LRP5 mutations in four patients with osteoporosis-pseudoglioma syndrome: identification of a 7.2-kb microdeletion using oligonucleotide tiling microarray.
Narumi S, Numakura C, Shiihara T, Seiwa C, Nozaki Y, Yamagata T, Momoi MY, Watanabe Y, Yoshino M, Matsuishi T, Nishi E, Kawame H, Akahane T, Nishimura G, Emi M, Hasegawa T
Am J Med Genet A. 2010 Jan;152A(1):133-40.
2010
http://onlinelibrary.wiley.com/doi/10.1002/ajmg.a.33177/abstract;jsessionid=5617475376D1BD9B442D3D330CCA6D88.f02t04
Tuning of apoptosis-mediator gene transcription in HepG2 human hepatoma cells through an adenosine signal.
Yang D, Yaguchi T, Lim CR, Ishizawa Y, Nakano T, Nishizaki
T.Cancer Lett. 2010 May 28;291(2):225-9. doi: 10.1016/j.canlet.2009.10.016. Epub 2009 Nov 8.
2010
https://www.sciencedirect.com/science/article/abs/pii/S0304383509006387?via%3Dihub
2009
Dicer is required for maintaining adult pancreas.
Morita, S, Hara, A, Kojima, I, Horii, T, Kimura, M, Kitamura, T, Ochiya, T, Nakanishi, K, Matoba, R, Matsubara, K. and Hatada, I.
PLoS One. 4 (2009) e4212.
2009
https://doi.org/10.1371/journal.pone.0004212
Transcriptional induction and translational inhibition of Arc and Cugbp2 in mice hippocampus after transient global ischemia under normothermic condition.
Otsuka N, Tsuritani K, Sakurai T, Kato K, Matoba R, Itoh J, Okuyama S, Yamada K, Yoneda Y.
Brain Res. 1287 (2009) 136-145.
2009
https://doi.org/10.1016/j.brainres.2009.06.050
Screening of potential molecular targets for colorectal cancer therapy.
Honma K, Takemasa I, Matoba R, Yamamoto Y, Takeshita F, Mori M, Monden M, Matsubara K and Ochiya T.
Int J Gen Med. 29 (2009) 243-257.
2009
https://doi.org/10.2147/IJGM.S5158
Genetic polymorphisms of paraoxonase-1 are associated with chronic kidney disease in Japanese women.
Ichikawa K, Konta T, Emi M, Toriyama S, Takasaki S, Ikeda A, Shibata Y, Takabatake N, Takeishi Y, Kato T, Kawata S, Kubota I
Kidney Int. 2009 Jul;76(2):183-9.
2009
https://doi.org/10.1038/ki.2009.97
Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis.
Mori S, Kou I, Sato H, Emi M, Ito H, Hosoi T, Ikegawa S
J Bone Miner Metab. 2009;27(2):213-6.
2009
https://link.springer.com/article/10.1007%2Fs00774-008-0031-9
Prediction of efficacy of anti-TNF biologic agent, infliximab, for rheumatoid arthritis patients using a comprehensive transcriptome analysis of white blood cells.
Tanino M, Matoba R, Nakamura S, Kameda H, Amano K, Okayama T, Nagasawa H, Suzuki K, Matsubara K, Takeuchi T.
Biochem Biophys Res Commun. 2009 Sep 18;387(2):261-5.
2009
http://www.sciencedirect.com/science/article/pii/S0006291X09013163
2008
A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells.
Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T.
FEBS J. 2008 Mar;275(6):1260-73. doi: 10.1111/j.1742-4658.2008.06287.x.
2008
http://onlinelibrary.wiley.com/doi/10.1111/j.1742-4658.2008.06287.x/abstract;jsessionid=2243B893C28CA8557A754877FB65B46C.f02t04
A functional polymorphism of the TNF-alpha gene that is associated with type 2 DM.
Susa S, Daimon M, Sakabe J, Sato H, Oizumi T, Karasawa S, Wada K, Jimbu Y, Kameda W, Emi M, Muramatsu M, Kato T
Biochem Biophys Res Commun. 2008 May 9;369(3):943-7. Epub 2008 Mar 6.
2008
http://www.sciencedirect.com/science/article/pii/S0006291X08004117
Association of CC chemokine ligand 5 genotype with urinary albumin excretion in the non-diabetic Japanese general population: the Takahata study.
Konta T, Emi M, Toriyama S, Ariumi H, Ishii M, Takasaki S, Ikeda A, Ichikawa K, Shibata Y, Takabatake N, Takeishi Y, Kato T, Kawata S, Kubota I
J Hum Genet. 2008;53(3):267-74. Epub 2008 Jan 24.
2008
https://link.springer.com/article/10.1007/s10038-008-0246-6
Association of genetic variations of genes encoding thrombospondin, type 1, domain-containing 4 and 7A with low bone mineral density in Japanese women with osteoporosis.
Mori S, Kou I, Sato H, Emi M, Ito H, Hosoi T, Ikegawa S
J Hum Genet. 2008;53(8):694-7. Epub 2008 May 17.
2008
https://doi.org/10.1007/s10038-008-0300-4
Common null variant, Arg192Stop, in a G-protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity.
Koyano S, Emi M, Saito T, Makino N, Toriyama S, Ishii M, Kubota I, Kato T, Kawata S
Hepatol Res. 2008 Jul;38(7):696-703. Epub 2008 Mar 4.
2008
http://onlinelibrary.wiley.com/doi/10.1111/j.1872-034X.2008.00327.x/abstract
Establishment of Rat Embryonic Stem Cells and Making of Chimera Rats.
Ueda S, Kawamata M, Teratani T, Shimizu T, Tamai Y, Ogawa H, Hayashi K, Tsuda H, Ochiya T.
PLoS One. 2008 Jul 30;3(7):e2800.
2008
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002800
Genetic association between aldehyde dehydrogenase 2 (ALDH2) variation and high-density lipoprotein cholesterol (HDL-C) among non-drinkers in two large population samples in Japan.
Wada M, Daimon M, Emi M, Iijima H, Sato H, Koyano S, Tajima K, Kawanami T, Kurita K, Hunt SC, Hopkins PN, Kubota I, Kawata S, Kato T
J Atheroscler Thromb. 2008 Aug;15(4):179-84.
2008
https://www.jstage.jst.go.jp/article/jat/15/4/15_E542/_article
Genomic approaches to bone and joint diseases. A genome-wide approach for analysis of polygenic diseases.
Sato H, Emi M
Clin Calcium. 2008 Feb;18(2):176-81.
2008
https://www.ncbi.nlm.nih.gov/pubmed/18245886
Novel amino linkers enabling efficient labeling and convenient purification of amino-modified oligonucleotides.
Komatsu, Y, Kojima, N, Sugino, M, Mikami, A, Nonaka, K, Fujinawa, Y, Sugimoto, T, Sato, K, Matsubara, K. and Ohtsuka, E.
Bioorg. Med. Chem. , 16, 941-949 (2008).
2008
http://www.sciencedirect.com/science/article/pii/S0968089607008565
Salt consumption-dependent association of the GNB3 gene polymorphism with type 2 DM.
Daimon M, Sato H, Sasaki S, Toriyama S, Emi M, Muramatsu M, Hunt SC, Hopkins PN, Karasawa S, Wada K, Jimbu Y, Kameda W, Susa S, Oizumi T, Fukao A, Kubota I, Kawata S, Kato T
Biochem Biophys Res Commun. 2008 Sep 26;374(3):576-80. Epub 2008 Jul 24.
2008
http://www.sciencedirect.com/science/article/pii/S0006291X08014137
A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells.
Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T.
FEBS J. 2008 Mar;275(6):1260-73. doi: 10.1111/j.1742-4658.2008.06287.x.
2008
https://febs.onlinelibrary.wiley.com/doi/full/10.1111/j.1742-4658.2008.06287.x
2007
Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray.
Iwahashi H, Kitagawa E, Suzuki Y, Ueda Y, Ishizawa YH, Nobumasa H, Kuboki Y, Hosoda H, Iwahashi Y.
BMC Genomics. 2007 Apr 5;8:95.
2007
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-8-95
Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes.
Takamura T, Honda M, Sakai Y, Ando H, Shimizu A, Ota T, Sakurai M, Misu H, Kurita S, Matsuzawa-Nagata N, Uchikata M, Nakamura S, Matoba R, Tanino M, Matsubara K, Kaneko S
Biochem Biophys Res Commun. 2007 Sep 21;361(2):379-84.
2007
http://www.sciencedirect.com/science/article/pii/S0006291X07014623
2006
Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue.
Kojima N, Sugino M, Mikami A, Nonaka K, Fujinawa Y, Muto I, Matsubara K, Ohtsuka E, Komatsu Y.
Bioorg. Med. Chem. Lett, 16, 5118-5121 (2006).
2006
http://www.sciencedirect.com/science/article/pii/S0960894X06008031
Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines.
Mikata R, Yokosuka O, Fukai K, Imazeki F, Arai M, Tada M, Kurihara T, Zhang K, Kanda T, Saisho H.
Int J Cancer. 2006, vol.119, pp1616-1622
2006
Arpc1b Gene Is a Candidate Prediction Marker for Choroidal Malignant Melanomas Sensitive to Radiotherapy.
Ken Kumagai, Yoshinori Nimura, Atsushi Mizota, Nobuyuki Miyahara, Mizuho Aoki, Yoshiya Furusawa, Masaki Takiguchi, Shuichi Yamamoto, and Naohiko Seki
Invest Ophthalmol Vis Sci, 2006, 47(6):2300-4
2006
Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression.
Shiraishi K, Yamasaki K, Nanba D, Inoue H, Hanakawa Y, Shirakata Y, Hashimoto K, Higashiyama S.
Oncogene. 2006 Jul 24; [Epub ahead of print]
2006
PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-independent prostate cancer proliferation.
Kikugawa T, Kinugasa Y, Shiraishi K, Nanba D, Nakashiro K, Tanji N, Yokoyama M, Higashiyama S.
Prostate. 2006 Jul 1;66(10):1092-9.
2006
Naked gene therapy of hepatocyte grouth factor for dextran sulfate sodium-induced colitis in mice.
T.Kanbe, R.Murai, T.Mukoyama, Y.Murawaki, K.Hashiguchi, Y.Yoshida, H.Tsuchiya, A.Kurimasa, K.Harada, K.Yashima, E.Nishimuki, N.Shabana, Y.Kishimoto, H.Kojyo, K.Miura, Y.Murawaki, H.Kawasaki, G.Shiota
Biochemical and Biophysical Research Communications, 345(2006) 1517-1525
2006
Characterization of Gene Expression Profiles of Metallothionein-Null Cadmium-Resistant Cells.
Hitomi Fujishiro, Satomi Okugaki, Sachi Nagao, Masahiko Satoh, and Seiichiro Himeno
Journal of Health Science, 52(3) 292-299(2006)
2006
Novel roles of osteopontin and CXC chemokine ligand 7 in the defence against mycobacterial infection.
V.Khajoee, M.Saito, H.Takada, A.Nomura, K Kusuhara, S.-I.Yoshida, Y.Yoshikai and T. Hara
Clinical & Experimental Immunology, Vol143, Issue 2, pp260, 2006
2006
Multiple primer extension by DNA polymerase on a novel plastic DNA array coated with a biocompatible polymer.
Kinoshita K, Fujimoto K, Yakabe T, Saito S, Hamaguchi Y, Kikuchi T, Nonaka K, Murata S, Masuda D, Takada W, Funaoka S, Arai S, Nakanishi H, Yokoyama K, Fujiwara K, Matsubara K.
Nucleic Acids Research, doi:10.1093/nar/gkl939, 2006.
2006
Microarray analysis of promoter methylation in lung cancers.
Masayuki Fukusawa・Mika Kimura・Sumiyo Mroita・Kenichi Matsubara・Sumitaka Yamanaka・Chiaki Endo・Akira Sakurada・Masami Sato・Takashi Kondo・Akira Horii・Hiroyuki Sasaki・Izuho hatada
J Hum Genet,51(4),(2006),368-374
2006
2005
High throughput purification of amino-modified oligonucleotides and its application to novel detection system of gene expression.
Kojima N, Sugino M, Mikami A, Nonaka K, Fujinawa Y, Ueda Y, Sato K, Ohtsuka E, Matsubara K, Komatsu Y.
Nucleic Acids Sym. Ser., 49, 181-182 (2005).
2005
https://academic.oup.com/nass/article-abstract/49/1/181/1070343/High-throughput-purification-of-amino-modified?redirectedFrom=fulltext
Distinct gene expression patterns of peripheral blood cells in hyper-IgE syndrome.
Tanaka T, Takada H, Nomura A, Ohga S, Shibata R, Hara T.
Clin Exp Immunol., 140(3), pp524-531, 2005
2005
Methylation-Associated Silencing of the Nuclear Receptor 1I2 Gene in Advanced-Type Neuroblastomas, Identified by Bacterial Artificial Chromosome Array-Based Methylated CpG Island Amplification.
Akiko Misawa, Jun Inoue, Yuriko Sugino, Hajime Hosei, Tohru Sugimoto, Fumie Hosoda, Misao Ohki, Issei Imoto and Johji Inazawa
Cancer Reserch, Vol.65, 10233-10242, 2005
2005
Serotonin and melatonin, neurohormones for homeostasis, as novel inhibitors of infections by the intracellular parasite chlamydia.
Mohd. Akhlakur Rahman, Yoshinao Azuma, Hajime Fukunaga, Tomoyuki Murakami, Kazurou Sugi, Hideto Fukushi, Koshiro Miura, Harumi Suzuki and Mutsunori Shirai
Journal of Antimicrobial Chemotherapy, 2005, 56(5):861-868
2005
Persistence of gene expression changes in noninflamed and inflamed colonic mucosa in ulcerative colitis and their presence in colonic carcinoma.
Yuji Toyama, Akira Mizoguchi, Kazushi Kimura, Toshimitsu Araki, Shigeyuki Yoshiyama, Kouhei Sakaguchi, Chikao Miki, Masato Kusunoki
World J Gastroenterol 2005;11(33):5151-5155
2005
Gene expression profiles in peripheral blood mononuclear cells from patients with subacute sclerosing panencephalitis using oligonucleotide microarray.
Megumi Takemoto, Ryutaro Kira, Koichi Kusuhara, Hiroyuki Torisu, Yasunari Sakai, Toshiro Hara
Journal of NeuroVirology, Vol11, No.3, 2005, pp299-305
2005
Recapitulation of in vivo gene expression during hepatic differentiation from murine embryonic stem cells.
Yusuke Yamamoto, Takumi Teratani, Hanako Yamamoto ,Gary Quinn, Sigenori Murata, Rieko Ikeda, Kenji Kinoshita, Kenichi Matsubara, Takashi Kato, Takahiro Ochiya
Hepatology, Volume 42, Issue 3 (September 2005), (p 558-567)
2005
Psychophysiological stress-regulated gene expression in mice
Shigenori Murata, Taeko Yoshiara, Chun Ren Lim, Maiko Sugino, Mitori Kogure, Tatsuya Ohnuki, Toshi Komurasaki, Kenichi Matsubara
FEBS Letters, 579: 2137-2142, 2005
2005
Genetic basis of phenotypic plasticity for predator-induced morphological defenses in anuran tadpole, Rana pirica, using cDNA subtraction and microarray analysis
Tsukasa Mori, Ikuei Hiraka, Youichi Kurata, Hiroko Kawachi, Osamu Kishida, Kinya Nishimura
Biochemical and Biophysical Research Communications 330 (2005) 1138-1145
2005
Recapitulation of In Vivo Gene Expressuib During Hepatic Differrentiation From Murine Embryonic Stem Cells
Yusuke Ymamoto, Takumi Teratani, Hanko Yamamoto, Gary Quinn, Sigenori Murata, Rieko Ikeda, Kenji Kinoshita, Kenichi Matsubara, Takashi Kato, and Takahiro Ochiya
HEPATOLOGY vol. 42, No.3, 2005
2005
2004
Synthesis and application of new amino modification analogues for functional oligonucleotide.
Komatsu Y, Kojima N, Nonaka K, Fujinawa Y, Sugino M, Mikami A, Hashida J, Ohtsuka E, Matsubara K
Nucleic Acids Sym. Ser., 48, 21-22 (2004)
2004
https://academic.oup.com/nass/article-lookup/doi/10.1093/nass/48.1.21
Hypergravity Induces Phosphorylation of p53 at Serine 15, but not an Expression of p53-downstream Genes
Kumio OKAICHI, Miwa IDE, Aya Usui, and Yutaro OKUMURA
J. Radiat. Res., 45, 399-403 (2004)
2004
MRP-1/CD9 gene transduction downregulates Wnt signal pathways
Cheng-long Huang, Dage Liu, Daiki Masuya, Kotaro Kameyama, Takashi Nakashima, Hiroyasu Yokomise, Masaki Ueno and, Masayuki Miyake
Oncogene, Volume 23, Number 45, pp7475-7483, 2004
2004
Overexpression of PDZK1 within the 1q12-q22 Amplicon Is Likely To Be Associated with Drug-Resistance Phenotype in Multiple Myeloma
Jun Inoue, Takemi Otsuki, Akira Hirasawa, Issei Imoto, Yoshinobu Matsuo, Shiroh Shimizu, Masafumi Taniwaki, and Johji Inazawa
American Journal of Pathology, Vol.165, No.1, 2004, pp71-81
2004
Prepro-tachykinin gene expression in the brain of the honeybee Apis mellifera
Hideaki Takeuchi, Akikazu Yasuda, Yoshimi Yasuda-Kamatani, Miyuki Sawata, Yuko Matsuo, Azusa Kato, Atsumi Tsujimoto, Terumi Nakajima, Takeo Kubo
Cell Tissue Res (2004) 316:281-293
2004
Identification of Differentially Expressed Genes Involved in Colorectal Carcinogenesis Using a cDNA Microarray
T. Komori, I. Takemasa, H. Higuchi, M. Yamasaki, M. Ikeda, H. Yamamoto, M. Ohue, S. Nakamori, M. Sekimoto, K. Matsubara and M. Monden
J Exp Clin Cancer Res. 2004 Sep;23(3):521-7
2004
Gene expression profiling of mouse postnatal cerebellar development using cDNA microarrays
Lim CR, Fukakusa A, Matsubara K.
Gene. 2004 May 26;333:3-13
2004
2003
Impairment of the DNA binding activity of the TATA-binding protein renders the transcriptional function of Rvb2p/Tih2p, the yeast RuvB-like protein, essential for cell growth
Ohdate, H., Lim, C.R., Kokubo, T., Matsubara, K., Kimata, Y. and Kohno, K.
J Biol Chem 2003 Apr 25;278(17):14647-56.
2003
cDNA microarray analysis of individual Duchenne muscular dystrophy patients
Noguchi S, Tsukahara T, Fujita M, Kurokawa R, Tachikawa M, Toda T, Tsujimoto A, Arahata K, Nishino I
Hum. Mol. Genetics, 12:595-600, 2003
2003
A Bayesian missing value estimation method for gene expression profile data
Shigeyuki Oba, Masa-aki Sato, Ichiro Takemasa, Morita Monden, Ken-chi Matsubara and Shin Ishii
Oxford Universiry Press Bioinformatics vol.19 nNo.16, 2003
2003
A novel feature of microsatellites in plants : a distribution gradient along the direction of transcription
Shigeo Fujimori, Takanori Washio, Kenichi Higo, Yasuhiro Ohtomo, Kazuo Murakami, Kenichi Matsubara, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Shoshi Kikuchi, Masaru Tomita
FEBS Letter 554, 2003
2003
DNA alterations during multi-step development of human hepatocellular carcinomas revealed by laser capture microdissection
Hisaki Nagai, Mitsuru Emi, Yoshie Terada, Masaru Baba, Masashi Shimizu, Noboru Konishi, Shuichi Kaneko, Kenichi Kobayashi, Yasuhiro umoto, Mohammed Ghazizadeh, Oichi Kawanami, Kenichi Matsubara
Hepatology Research Hepatology Research 26, 2003
2003
Collection, Mapping, and Annotation of Over 28,000 cDNA Clones from japonica Rice
National Institute of Agrobiological Sciences Rice Full-Length cDNA Project Team: Shoshi Kikuchi, Kouji Satoh, Toshifumi Nagata, Nobuyuki Kawagashira, Koji Doi, Naoki Kishimoto, Junshi Yazaki, Masahiro Ishikawa, Hitomi Yamada, Hisako Ooka, Isamu Hotta, Keiichi Kojima, Takahiro Nmki, Eisuke Ohneda, Wataru Yahagi, Kohji Suzuki, Chao Jie Li, Kenji Ohtsuki, Toru Shishiki; Foundation of Advancement of International Science Genome Sequencing & Analysis Group: Yasuhiro Otomo, kazuo Murakami, Yoshiharu Iida, Sumio Sugano, Tatsuto Fujinura, Yutaka Suzuki, Yuki Tsunoda, Takashi Kurosaki, Takeko Kodama, Hiromi Masuda, Michie Kobayashi, Quihong Xie, Min Lu, Ryuya Narikawa, Akio Sugiyama, Kouichi Mizuno, Satoko Yokomizo, JunkoNiikura, Rieko Ikeda, Junya Ishibbiki, Midori Kawamata, Akemi Yoshimura, Junichirou Miura, takahiro Kusumegi, Mitsuru oka, Riasaa Ryu, Mariko Ueda, Kenichi Matsubara; RIKEN: Jun Kawai, Piero Carninci, Jun Adachi, Katsunori Aizawa, Takahiro Arakawam Shiro Fukuda, Ayako Hara, Wataru Hasgudume, Norihito Hayatsu, Koichi Imotani, Yoshiki Ishii, Masayoshi Itoh, Ikuko Kagawa, Shinji Kondo, Kedeaki Konno, Ai Miyazakim Naoki Osatot, Yoshimi Ota, Rintaro Saito, Daisuke Sasaki, Kenjiro Sato, Kazuhiro Shibata, AkiraShinagawa, Toshiyuki Shiraki, Masayasu Yoshino, Yoshihide Hayashizaki
Science, vol. 301, No.5631, 2003
2003
2002
Identification of genes expressed preferentially in the honeybee mushroom bodies by combination of differential display and cDNA microarray
Takeuchi H, Fujiyuki T, Shirai K, Matsuo Y, Kamikouchi A, Fujinawa Y, Kato A, Tsujimoto A, Kubo T.
FEBS Letters, 513:230-234, 2002
2002
A microarray-based method for detecting methylated loci.
Hatada I, Kato A, Morita S, Obata Y, Horii A, Sato M, Sakurada A, Nagaoka K, Tsujimoto A, Matsubara K., J. Hum.
Genetics, 47:448-451, 2002
2002
In vitro selection of hairpin ribozymes activated with short oligonucleotides
Komatsu, Y., Nobuoka, K., Karino-Abe, N., Matsuda, A. and Ohtsuka, E
Biochemistry, 41, 9090-9098 (2002).
2002
Expression profile of active genes in the human pituitary gland
S Tanaka, K Tatsumi, K Okubo, K Itoh, S Kawamoto, K Matsubara and N Amino
Journal of Molecular Endocrinology No. 28, 2002
2002
Modulation of polyglutamine-induces cell death by genes idenitified by expression profiling
Hiroko Kita, Jenny Carmicheal, Jina Swartz, Shizuko Muro, Andreas Wyttenbach, Kenichi Matsubara, David C. Rubinsztein and Kikuya Kato
Oxford Universiry Press Human Molecular Genetics, 2002, vol,11, no. 19
2002
Molecular classification of primary breast tumors possessing distinct prognostic properties
Kyoko Iwao, Ryo Matoba, Noriko Ueno, Akiko Ando, Yasuo Miyoshi, Kenichi Matsubra, Shinzaburo Noguchi and Kikuya Kato
Oxford Universiry Press Human Molecular Genetics, 2002, vol,11, no. 2
2002
Missing Value Estimation Using Mixture of PCAs
Shigeyuki Oba, Masa-aki Sato, Ichiro Takemasa, Morita Monden, Kenichi Matsubara and Shin Ishii
Artificial Neural Networks ICANN 2002
2002
2000
Construction of new ribozymes requiring short regulator oligonucleotides as a cofactor.
Komatsu, Y., Yamashita, S., Kazama, N., Nobuoka, K. and Ohtsuka, E.
J. Mol. Biol. 299, 1231-1243 (2000).
2000
Regulation of ribozyme cleavage activity by oligonucleotides. “Catalytic Nucleic Acid Protocols”
Komatsu, Y. and Ohtsuka, E.
Methods in Molecular Biology 252, 165-177.